The first battle of the U.S.- Mexican War took place on April 25, 1846. The Mexican Cavalry, which comprised 2,000 soldiers, attacked a U.S. scouting party of 63 soldiers led by General Zachary Taylor. Nearly a dozen U.S. soldiers were killed in the battle. Over the course of the war, nearly 38,000 soldiers died. The deaths related to actual combat were approximately 2,000; the rest were attributed to disease in the U.S. camps. The war ended in 1848 when U.S. troops entered Mexico City.

Read about the events of the war in the timeline map at the link provided below.

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Date of Event Summary of Event U.S. Leaders Mexican Leaders Impact on the U.S.-Mexican War
May 1846
May 8-9, 1846
February 22-23, 1847
September 12-13, 1847
September 14, 1847
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Date of Event Summary of Event U.S. Leaders Mexican Leaders Impact on the U.S.-Mexican War
May 1846 U.S. Army crosses the Rio Grande and occupies Matamoros General Zachary Taylor General Mariano Arrista U.S. declares war on Mexico
May 8-9, 1846 U.S. Army wins the battles of Palo Alto and Resaca General Zachary Taylor General Mariano Arrista Mexican Army is forced back across the Rio Grande
February 22-23, 1847 U. S. Army defeats Mexican Army at the Battle of Buena General Zachary Taylor Santa Anna Mexican troops retreat south
September 12-13, 1847 Mexican soldiers defend the Castle of Capultopec against the U.S. General Winfield Scott Santa Anna Mexican army falls to the U.S. troops
September 14, 1847 U.S. occupies Mexico City General Winfield Scott Santa Anna The occupation of Mexico City gives the U.S. Army an advantage in the war
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After capturing Mexico City, the United States was able to bring the war to a close. Mexico's leader, Santa Anna, was stripped of his command and exiled to Jamaica. Negotiations began to end the war peacefully.